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Guides

Hyaluronic Acid Guide: The Moisture Miracle of Skincare

What is hyaluronic acid and how does it work? Different molecular weights, proper usage techniques, and the best hyaluronic acid serum recommendations.

January 22, 202411 min readBy: Beauty Editor
Dry SkinOily SkinCombination SkinNormal SkinSensitive Skin
Hyaluronic acid serum drop
Hyaluronic acid serum drop
Affiliate Disclosure: Some links in this article are affiliate links. We may earn a commission from your purchases. This does not affect the objectivity of our content.

Hyaluronic Acid Guide: The Superhero of Skin Hydration

Hyaluronic acid is one of the most popular and well-researched ingredients in the skincare world. With its capacity to hold 1000 times its weight in water, this natural molecule is the most effective way to meet your skin's hydration needs.

In this comprehensive guide, we'll detail what hyaluronic acid is, its different types, proper usage techniques, and the best product recommendations. For serum selection suitable for your skin type, check out our Skin Type Determination Guide.

Affiliate Disclosure
Some links in this article are affiliate links. We may earn a commission from purchases made through these links. This does not affect our opinions or recommendations about the products. Our recommendations are always based on honest and unbiased evaluations.

What is Hyaluronic Acid?

Hyaluronic acid (HA) is a glycosaminoglycan naturally found in our body. It's found in the highest concentrations in skin, eyes, and joint fluid. In the skin, it concentrates in the dermis layer (middle layer) and maintains the skin's moisture balance.

Natural HA Loss

Our body's hyaluronic acid production decreases with age. At 50, we drop to approximately half of the HA levels we had at birth. This is one of the main causes of skin dryness, fine lines, and loss of elasticity.

Properties of Hyaluronic Acid

Hyaluronic Acid

The skin's natural moisturizing factor. A glycosaminoglycan structure with humectant properties. Can hold 1000 times its weight in water.

Benefits
  • Intense and long-lasting hydration
  • Plumps wrinkles and fine lines
  • Strengthens skin barrier
  • Suitable for all skin types
  • Excellent compatibility with other actives
  • Non-irritating, safe for sensitive skin
Suitable Skin Types
All skin typesDry skinSigns of agingDehydrated skin
Cautions
Rare: those with HA allergy

How Does Hyaluronic Acid Work on Skin?

Hyaluronic acid works as a humectant. This means it draws water molecules from the surrounding moist environment (air or deeper layers of skin) and holds them on the skin's surface.

Moisture-Drawing Mechanism

  1. Water attraction: HA molecules draw water around them like a "magnet"
  2. Moisture retention: The drawn water is held in the upper layers of skin
  3. Plumping: Water-filled cells make skin look more plump and smooth
  4. Barrier support: Moisture balance helps keep the skin barrier healthy
Warning

Hyaluronic acid can draw moisture from your skin in dry environments. In very dry climates or winter, sealing HA serum with a moisturizer is critically important.

Molecular Weights: Which is Better?

Hyaluronic acid comes in different molecular weights. Each size has its own unique advantages.

Hyaluronic Acid Molecular Sizes

1
High Molecular Weight HA (HMW-HA)

Large molecules. Stays on skin surface, cannot penetrate deep.

Forms protective film on surface, provides instant plumping and softness. Prevents moisture loss.

2
Medium Molecular Weight HA (MMW-HA)

Medium-sized molecules. Penetrates upper layers of epidermis.

Balanced hydration. Both surface and slight depth effect.

3
Low Molecular Weight HA (LMW-HA)

Small molecules. Reaches deeper layers of skin.

Deep hydration, long-lasting effect, anti-aging benefits.

4
Hydrolyzed Hyaluronic Acid

Smallest fragments. Can penetrate to dermis layer.

Deepest effect, potential to support collagen production.

Expert Opinion
— Formulation Expert

The most effective hyaluronic acid serums contain multiple molecular weights. This "multi-molecular" approach provides both surface and deep hydration. A single size doesn't offer full benefits.

Sodium Hyaluronate vs Hyaluronic Acid

You may see both in ingredient lists:

  • Hyaluronic Acid: Pure form
  • Sodium Hyaluronate: Salt form, smaller molecule, better penetration
Tip

Sodium Hyaluronate is more stable than pure HA and absorbs more easily into skin. Seeing "Sodium Hyaluronate" in ingredient lists is generally a good sign.

Benefits of Hyaluronic Acid

1. Intense Hydration

HA's most known benefit. Brings life to dry, tight, and lifeless skin.

  • Instant moisture boost
  • All-day hydration (with proper use)
  • Reduces signs of dehydration

2. Anti-Aging Effect

Moisture-filled cells make wrinkles look less noticeable.

  • "Fills" fine lines
  • Plumps skin
  • Delays signs of aging

3. Skin Barrier Support

Healthy moisture balance supports keeping the skin barrier strong.

  • Reduces TEWL (transepidermal water loss)
  • Protection from external factors
  • Reduces sensitivity

4. Universal Compatibility

HA can be used by almost everyone and in every situation.

  • All skin types
  • Including sensitive skin
  • Safe during pregnancy and breastfeeding
  • Compatible with other actives

Hyaluronic Acid Skin Type Compatibility

Dry SkinPerfect
Oily SkinPerfect
Combination SkinPerfect
Normal SkinPerfect
Sensitive SkinPerfect
PerfectGoodNeutralUse with CautionNot Suitable

Hyaluronic Acid Usage

Pros
  • Safe for all skin types
  • Non-irritating
  • Excellent compatibility with other actives
  • Instant and long-term benefits
  • Suitable for all age groups
  • Safe during pregnancy
Cons
  • Can have reverse effect in dry environments
  • Not sufficient alone (must be sealed with moisturizer)
  • Some formulas can feel sticky
  • Very pure forms can be expensive

Proper Usage Techniques

Proper usage technique is critical to get maximum benefit from hyaluronic acid.

1. Application on Damp Skin

Most Important Rule

NEVER apply hyaluronic acid to dry skin! Apply to damp or wet skin. When applied to dry skin, HA can draw moisture from your skin.

Correct application:

  1. Wash your face
  2. While your skin is still damp (without fully drying)
  3. Apply HA serum
  4. Immediately seal with moisturizer

2. Locking with Moisturizer

HA alone is not sufficient. An occlusive layer (moisturizer) is needed to lock the drawn moisture.

Recommended order:

  1. Cleanser
  2. Toner (optional, adds light moisture)
  3. Hyaluronic acid serum (on damp skin)
  4. Other serums (if any)
  5. Moisturizer (essential!)
  6. SPF (morning)

3. Layering Technique

For dry skin, "7 skin method" or HA layering:

  1. Apply first layer of HA serum
  2. Wait for absorption
  3. Apply second layer
  4. Finish with moisturizer
Tip

Applying multiple layers is more effective than using too much product at once. Skin absorbs each layer separately.

4. Pay Attention to Environmental Humidity

  • Humid environment: HA draws moisture from air, gives it to your skin
  • Dry environment: HA can draw moisture from your skin!

Dry environment solutions:

  • Always use moisturizer
  • Use a room humidifier
  • Support with occlusive products (vaseline, shea butter)

Top 10 Hyaluronic Acid Serums

1. The Ordinary Hyaluronic Acid 2% + B5

✨
The Ordinary

The Ordinary Hyaluronic Acid 2% + B5

4.5 (8765 reviews)

2% hyaluronic acid (low, medium, high molecular weight) + vitamin B5. Intense hydration, lightweight formula. Best-selling HA serum.

Dry SkinOily SkinCombination SkinNormal SkinSensitive Skin

✓ Best value for money

$8View on Amazon

The Ordinary HA

Pros
  • Very affordable price
  • 3 different molecular weights
  • Extra hydration with B5
  • Lightweight, fast-absorbing formula
Cons
  • Stickiness for some users
  • May be insufficient for very dry skin

2. La Roche-Posay Hyalu B5 Serum

✨
La Roche-Posay

La Roche-Posay Hyalu B5 Serum

4.6 (3456 reviews)

2 types of hyaluronic acid + vitamin B5 + madecassoside. Anti-aging and intense hydration. Tested for sensitive skin.

Dry SkinNormal SkinSensitive Skin

✓ Safe for sensitive skin

$40View on Amazon

3. Vichy Mineral 89

✨
Vichy

Vichy Mineral 89 Hyaluronic Acid Booster

4.7 (5678 reviews)

89% Vichy mineralizing water + hyaluronic acid. Strengthens skin barrier, plumps. For all skin types.

Dry SkinOily SkinCombination SkinNormal Skin

✓ Mineral water richness

$30View on Amazon

4. COSRX Hyaluronic Acid Intensive Cream

✨
COSRX

COSRX Hyaluronic Acid Intensive Cream

4.5 (2345 reviews)

Hyaluronic acid + vitamin B5 + allantoin. Cream texture, intense hydration. K-Beauty favorite.

Dry SkinNormal Skin

✓ HA in cream texture

$22View on Amazon

5. Paula's Choice Hyaluronic Acid Booster

✨
Paula's Choice

Paula's Choice BOOST Hyaluronic Acid Booster

4.5 (1890 reviews)

Multi-molecular hyaluronic acid + ceramides. Booster formula that can be added to other products. Research-backed.

Dry SkinOily SkinCombination SkinNormal Skin

✓ Booster formula

$42View on Amazon

6. SkinCeuticals H.A. Intensifier

✨
SkinCeuticals

SkinCeuticals H.A. Intensifier

4.6 (1234 reviews)

10% proxylane + 2% hyaluronic acid combination. Increases skin's own HA production by 30%. Premium anti-aging.

Dry SkinNormal Skin

✓ Increases HA production

$120View on Amazon
Expert Opinion
— Dermatology Expert

SkinCeuticals H.A. Intensifier doesn't just provide HA, it also stimulates the skin's own hyaluronic acid production. This "inside-out" approach offers long-term anti-aging benefits.


7. Neutrogena Hydro Boost Water Gel

✨
Neutrogena

Neutrogena Hydro Boost Water Gel

4.4 (6789 reviews)

Hyaluronic acid-based water gel moisturizer. Oil-free, lightweight formula. Drugstore brand accessibility.

Oily SkinCombination SkinNormal Skin

✓ Drugstore favorite

$20View on Amazon

8. Hada Labo Gokujyun Premium Lotion

✨
Hada Labo

Hada Labo Gokujyun Premium Hyaluronic Acid Lotion

4.7 (4567 reviews)

5 types of hyaluronic acid + urea. Iconic product of Japanese skincare. Lotion = essence texture.

Dry SkinNormal Skin

✓ 5 HA combination

$16View on Amazon

9. Drunk Elephant B-Hydra Intensive Hydration Serum

✨
Drunk Elephant

Drunk Elephant B-Hydra Intensive Hydration Serum

4.5 (1567 reviews)

Pro-vitamin B5 + watermelon rind + pineapple ceramide. Oil-free, gel texture. Clean beauty approach.

Oily SkinCombination SkinNormal Skin

✓ Clean beauty formula

$48View on Amazon

10. Isntree Hyaluronic Acid Toner

✨
Isntree

Isntree Hyaluronic Acid Toner

4.6 (2890 reviews)

50% hyaluronic acid complex. Low pH, toner format. K-Beauty hidden favorite.

Dry SkinOily SkinCombination SkinNormal Skin

✓ HA in toner format

$18View on Amazon

Hyaluronic Acid Combinations

Perfect Partners

Hyaluronic acid works excellently with other active ingredients. Find more information about these combinations in our Vitamin C Serum Guide and Retinol Usage Guide articles.

Safe Combinations with HA

Vitamin C

Hydration + antioxidant protection.

HA increases vitamin C penetration. Brightening and hydration together.

Niacinamide

Barrier strengthening + sebum control.

Perfect compatibility, all skin types.

Retinol

Anti-aging + moisture support.

HA balances retinol's drying effect.

Ceramides

Moisture attraction + barrier repair.

Ideal combination: HA draws moisture, ceramides lock it.

AHA/BHA

Exfoliation + moisture compensation.

Compensates moisture loss after acids.

All Combinations Are Safe

Hyaluronic acid has no special "avoid" combination. It can be safely used with almost any active. This makes it a "universal" skincare ingredient.

Frequently Asked Questions

Can hyaluronic acid be used every day?

Yes, it can be used morning and evening. HA is non-irritating and safe for daily use. It can be included in all routines.

Does hyaluronic acid harm skin?

No, HA is a natural component and harmless. However, in dry environments, if used without being applied to damp skin and without sealing with moisturizer, it can draw moisture from skin.

Are hyaluronic acid and sodium hyaluronate the same?

Similar but slightly different. Sodium hyaluronate is the salt form of HA. It absorbs more easily into skin due to its smaller molecular structure. Both are effective.

Does hyaluronic acid remove wrinkles?

It doesn't completely remove wrinkles but makes them less visible by plumping. For real anti-aging, combination with retinol or peptides is recommended. For detailed information about retinol, see our Retinol Usage Guide.

Is hyaluronic acid suitable for oily skin?

Absolutely yes! HA provides oil-free hydration. Oily skin can also be dehydrated and HA solves this problem. Lightweight, gel-based formulas should be preferred.

When will I see results?

Instant: Plumpness and softness is felt 1-2 weeks: Improvement in moisture balance 4-6 weeks: Reduction in fine lines (with regular use)

Is hyaluronic acid safe during pregnancy?

Yes, hyaluronic acid can be safely used during pregnancy and breastfeeding. It poses no risk as it's a substance naturally found in our body.

Conclusion

Hyaluronic acid is one of the most fundamental and indispensable ingredients in skincare. Suitable for all skin types, non-irritating, and perfectly compatible with other actives, this ingredient should be in every routine.

Our Recommendations:

  • Budget-Friendly: The Ordinary Hyaluronic Acid 2% + B5
  • Sensitive Skin: La Roche-Posay Hyalu B5
  • Oily Skin: Neutrogena Hydro Boost
  • Premium Anti-Aging: SkinCeuticals H.A. Intensifier
  • K-Beauty: Hada Labo Gokujyun Premium

Reminders:

  • Apply to damp skin
  • Seal with moisturizer
  • Be careful in dry environments
Golden Rule

Hyaluronic acid is your skin's best friend when used correctly. Apply to damp skin, lock with moisturizer, and make it an essential part of your daily routine.


If you found this guide helpful, check out our Vitamin C Serum Guide, Skin Type Determination Guide, and Vitamin C Serum Review articles.

Hyaluronic Acid Serums

Compare the most popular hyaluronic acid products

View on Amazon

* This is an affiliate link. We may earn a commission from your purchases.

#hyaluronic acid#serum#moisturizer#anti-aging#skincare#hydration

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